Table 2
Comparison of next-generation sequencing instruments
| Instrument | Amplification method | Sequencing method | Current max output | |
 | Roche GS-FLX | Emulsion PCR | Pyrosequencing | 1.5M reads/run (1 day) 500 bases/read |
 | Life Technologies Ion Torrent | Emulsion PCR | PostLight sequencing | 100k reads/run (2 h) 100 bases/read |
 | Life Technologies SOLiD 5500XL | Emulsion PCR | Sequencing by ligation | 4G reads/run (7 days) 75 bases/run |
 | Illumina HiSeq 2000 | Bridge amplification | Sequencing by synthesis | 6G reads/run (8 days) 100 bases/read |
 | Pacific Biosciences | Single molecule | Real-time sequencing | 100k reads/run (2 h) >1000 bases/run |