Patients characteristics (n=139)
| n (%)* † | |||
| All cohort | Familial cases | Sporadic cases | |
| Number of cases | 139 | 95 | 44 |
| Type of families | |||
| n | 68 | ||
| Consanguineous family | 53 (77.9) | NA | |
| Non-consanguineous multiplex family | 15 (22.1) | NA | |
| Ethnic origin | |||
| n | 134 | 68 families | 39 |
| North Africa | 31 (23.1) | 21 (30.9) | 5 (12.8) |
| Middle-East | 36 (26.9) | 23 (33.8) | 4 (10.3) |
| Europe | 46 (34.3) | 13 (19.1) | 26 (66.7) |
| Other | 21 (15.7) | 11 (16.2) | 4 (10.3) |
| Renal histological lesions | |||
| n | 129 | 64 families | 44 |
| FSGS | 98 (76.0) | 50 (78.1) | 28 (63.6) |
| DMS | 25 (19.4) | 10 (15.6) | 14 (31.8) |
| Other | 6 (4.7) | 4 (6.3) | 2 (4.5) |
| Age at onset of NS (months) | |||
| n | 127 | 86 | 41 |
| Median (range) | 23.0 (0–373) | 24.0 (0–373) | 23.0 (0–81) |
| Mean±SE | 46.2±5.7 | 55.7±8.1 | 26.4±3.4 |
| ESKD | |||
| n | 131 | 88 | 43 |
| Number of patients reaching ESKD | 76 (58.0) | 47 (53.4) | 29 (67.4) |
| Age at onset of ESKD (months) | |||
| n | 75 | 46 | 29 |
| Median (range) | 68.0 (0.5–264) | 81.0 (4–264) | 60.0 (0.5–139) |
| Mean±SE | 79.7±7.1 | 94.7±10.4 | 55.9±5.7 |