Genotype distributions of the three ABCC4 single nucleotide polymorphisms (SNPs) in cases and controls
| Genotype | Cases | |||||||
| Dutch | UK + Australia | All cases | Controls | |||||
| n | % | n | % | n | % | n | % | |
| a) rs7986087 | ||||||||
| 11 | 173 | 90.58 | 240 | 87.59 | 413 | 88.8 | 217 | 95.44 |
| 12 | 16 | 8.38 | 31 | 11.31 | 47 | 10.1 | 8 | 3.56 |
| 22 | 2 | 1.05 | 3 | 1.09 | 5 | 1.1 | 0 | 0 |
| Total | 191 | 274 | 465 | 225 | ||||
| b) rs7320375 | ||||||||
| 11 | 171 | 89.53 | 240 | 87.59 | 411 | 88.4 | 217 | 96.44 |
| 12 | 18 | 9.42 | 31 | 11.31 | 49 | 10.5 | 8 | 3.56 |
| 22 | 2 | 1.05 | 3 | 1.09 | 5 | 1.1 | 0 | 0 |
| Total | 191 | 274 | 465 | 225 | ||||
| c) rs7329490 | ||||||||
| 11 | 175 | 92.59 | 250 | 87.72 | 425 | 89.7 | 217 | 96.44 |
| 12 | 12 | 6.35 | 32 | 11.23 | 44 | 9.3 | 8 | 3.56 |
| 22 | 2 | 1.06 | 3 | 1.05 | 5 | 1.1 | 0 | 0 |
| Total | 189 | 285 | 474 | 225 | ||||
Cases from the US cohorts were not included for this analysis due to the low proportion of individuals of European descent in these cohorts.