Table 1

Analysis by transmission disequilibrium testing of eight single nucleotide polymorphisms (SNPs) within the 1-LOD drop interval defining the Chr 13q linkage region significant at p<0.01 from the genome-wide association study (GWAS)

SNP	Chr band	Position	Gene	GWAS study				GWAS study + all remaining samples^*
SNP	Chr band	Position	Gene	Cases	Controls	p Value	OR	p Value	OR	95% CI
rs7320375	13q32.1	94709934	ABCC4	0.058	0.020	0.0059	2.97	0.000088	2.00	1.41 to 2.83
rs7986087	13q32.1	94713746	ABCC4	0.054	0.020	0.0062	2.74	0.0003	1.98	1.38 to 2.83
rs11070146	13q32.1	95098788	DZIP1	0.116	0.051	0.0015	2.45	0.04	1.25	1.01 to 1.55
rs11070147	13q32.1	95098938	DZIP1	0.117	0.051	0.0014	2.47	0.07	1.22	0.99 to 1.51
rs285032	13q32.1	97584534	FARP1	0.43	0.59	0.0004	0.52	0.53	0.96	0.84 to 1.10
rs9513515	13q32.3	98394451	DOCK9	0.471	0.408	0.0023	1.30	0.20	1.10	0.95 to 1.27
rs9557096	13q32.3	98401880	DOCK9	0.471	0.409	0.0031	1.29	0.09	1.13	0.98 to 1.30
rs4772360	13q33.1	1.01E+08	VGCNL1	0.116	0.135	0.0080	0.84	0.18	0.89	0.75 to 1.06

↵* 1177 KD subjects and associated family members, total=3010 subjects.