Table 3 Frequency of a homozygous CFHR1 deletion according to the susceptibility factor and comparison of each subgroup with the control population using a χ2 test
Frequency of homozygous CFHR1 deletion (%) in each subgroupχ2p Value
Total cohort12.45.240.022
No factor identified4.80.33NS
CFH mutation2.60.002NS
FI mutation156.450.011
MCP mutation00.50NS
C3 mutation6.30.31NS
Combined mutations00.20NS
Anti-FH IgG92.964.45<0.0001
Cohort without anti-FH IgG cases5.50.77NS
Cohort without anti-FH IgG nor FI cases3.50.07NS
Control population2.9