Table 1 Determination of the number of CFHR1 alleles according the previously identified susceptibility factor in the French atypical haemolytic uraemic syndrome (aHUS) cohort (nā=ā177 patients) % (n) | 0 allele | 1 allele | 2 alleles |
Total cohort | 12.4 (22) | 19.8 (35) | 68 (120) |
No factor identified | 4.7 (3) | 26.6 (17) | 68.8 (43) |
CFH mutation | 2.6 (1) | 10.5 (4) | 86.8 (33) |
CFI mutation | 18.2 (4) | 27.3 (6) | 54.5 (12) |
MCP mutation | 0 | 6.25 (1) | 94 (16) |
C3 mutation | 6.3 (1) | 31 (5) | 62.5 (10) |
Combined mutations | 0 | 29 (2) | 71 (5) |
Anti-FH IgG | 93 (13) | 0 | 7 (1) |
Normal population | 2.8 (2) | 11.4 (8) | 85.7 (60) |