Prevalences of holoprosencephaly (HPE) types
| HPE type | Patients with mutations in ZIC2, n (%) | Probands with mutations in ZIC2, n (%) | Patients with deletions of ZIC2, n (%) |
| Alobar | 28 (20) | 26 (25) | 5 (31) |
| Semilobar | 48 (34) | 45 (44) | 3 (19) |
| Lobar | 11 (8) | 10 (10) | 1 (6) |
| MIHV | 5 (4) | 5 (5) | 0 (0) |
| Microform | 6 (4) | 0 | 0 (0) |
| None | 7 (5) | 0 | 0 (0) |
| Unknown | 36 (26) | 17 (17) | 7 (44) |
| Total | 141 | 103 | 16 |
MIHV, middle interhemispheric variant.