Centre | No. | Age (years) | Mean | SM | MM | Bilateral | Contra-lateral | BRCA1/2 | Women years f/u | Expected cancers | Sequential series | Information on RRO <50 years | Median follow-up (years) (completeness) |
Manchester | 245 | 21–60 | 41 | 27 | 218 | 179 | 66 | 87 | 1670.2 | 16.82 | Yes | 58/245 (24%) | 7.3 (C) |
Edinburgh | 121 | 24–72 | 45 | 67 | 53 | 30 | 91 | 18 | 464.2 | 3.84 | Yes | 11/121 (9%) | 4.7 (no follow-up on 9) |
Aberdeen | 22 | 33–57 | 43.8 | 6 | 16 | 12 | 10 | 4 | 74 | 0.6 | Yes | 7/22 (32%) | 8.3 (one lost |
Leiden | 35 | 20–53 | 38.5 | 23 | 12 | 31 | 4 | 24 | 267 | 3.17 | Yes | Not available | 9.2 (C) |
Dusseldorf | 8 | 29–46 | 37.5 | 3 | 5 | 7 | 1 | 2 | 85.3 | 0.59 | Yes | 2/8 (25%) | 9.6 (C) |
Oslo | 28 | 27–59 | 40 | 11 | 17 | 24 | 4 | 13 | 299.5 | 3.18 | Yes | Yes 6/28 (21%) | 11.7 (C) |
Southampton | 33 | 32–57 | 43.8 | 16 | 16 | 9 | 24 | 14 | 165.7 | 1.94 | Yes | Not complete | 7.3 (one lost |
Belfast | 22 | 28–57 | 41.5 | 22 | 0 | 9 | 13 | 11 | 99 | 1.25 | Yes | 3/22 (13%) | 7.2 (C) |
Guys | 32 | 26–56 | 40 | 23 | 5 | 12 | 20 | 25 | 179.9 | 2.5 | Yes | 10/32 (31%) | 7.1 (C) |
Paris | 4 | 28–51 | 40.5 | 2 | 2 | 1 | 3 | 4 | 40.9 | 0.71 | Yes | 3/4 (75%) | 10.2 (C) |
Total | 550 | 21–72 | 200 | 346 | 314 | 236 | 202 | 3334 | 34.44 | 100/492 (20%) | 7.5 |
C, complete follow-up; f/u, follow-up; MM, modified mastectomy (includes subcutaneous, and skin sparing); SM, simple mastectomy.