| Organ system | Males (n = 699) | Females (n = 754) | Total (n = 1453) | |||
| With signs/symptoms, % | Age at onset, years | With signs/symptoms, % | Age at onset, years | With signs/symptoms, % | Age at onset, years | |
| Neurological | 75 | 15.1 (15.0) | 61 | 20.9 (17.9) | 68 | 17.9 (16.6) |
| Cardiac | 60 | 29.2 (14.4) | 50 | 34.5 (17.6) | 55 | 31.6 (16.1) |
| Ocular | 58 | 29.2 (15.1) | 49 | 31.9 (18.3) | 53 | 30.5 (16.8) |
| Gastrointestinal | 57 | 22.2 (16.1) | 45 | 26.8 (19.2) | 51 | 24.3 (17.7) |
| Dermatological | 66 | 20.0 (15.4) | 37 | 30.8 (19.0) | 51 | 24.3 (17.7) |
| General | 59 | 18.7 (15.9) | 44 | 26.1 (19.0) | 51 | 21.8 (17.7) |
| Auditory | 56 | 29.0 (15.3) | 44 | 33.3 (19.1) | 50 | 31.0 (17.2) |
| Renal | 59 | 32.6 (12.7) | 38 | 38.5 (16.2) | 48 | 35.0 (14.5) |
| Musculoskeletal | 39 | 26.9 (16.8) | 34 | 34.7 (18.4) | 36 | 30.5 (17.9) |
| Vascular | 35 | 34.5 (12.9) | 25 | 41.7 (16.4) | 30 | 37.4 (14.9) |
| Psychiatric | 27 | 32.4 (15.3) | 23 | 36.5 (17.0) | 25 | 34.4 (16.2) |
| Respiratory | 29 | 32.9 (17.3) | 21 | 36.3 (20.5) | 24 | 34.3 (18.7) |
| Cerebrovascular | 25 | 31.3 (15.2) | 21 | 36.4 (18.1) | 23 | 33.7 (16.8) |
| Endocrinological | 5 | 31.4 (20.4) | 8 | 42.1 (17.9) | 7 | 39.0 (19.1) |
| Genital | 6 | 35.0 (17.9) | 1 | 38.6 (16.7) | 4 | 35.7 (17.5) |
Data are mean (SD) unless otherwise specified.