Table 5

Adjustments performed in the scores of index cases using the Manchester scoring system including pathology and receptor status

Index BRCA1/2 negativeBRCA1 indexBRCA2 index
Number with upward adjustment288 (33%)99 (80%)52 (49%)
Number with downward adjustment492 (57%)13 (10%)42 (40%)
Number with no change in score89 (10%)12 (10%)12 (11%)
Total cases869 (100%)124 (100%)106 (100%)