Table 4

Prior and adjusted risk for spinal muscular atrophy carrier status when two or three SMN1 copies are detected by quantitative assays

EthnicityPrior risk†Adjusted risk
2 copies3 copies*
Ashkenazi Jewish1:411:3501:4000
African American1:661:1211:3000
  • *The risk estimates were rounded to two significant digits due to approximations in their calculations

  • †Prior risk is the probability of having any carrier genotype (1+0, 1+1D, 2+0 and 2+1D).