Patient | 1 | 2 | 3 | 4 | 5 | 6 | ||||||
Sex | Male | Female | Female | Female | Male | Female | ||||||
Age* | 3 years | 16 months | 8.5 years | 9.5 years | 5.5 years | 26 months | ||||||
Questions | t1 | t2 | t1 | t2 | t1 | t2 | t1 | t2 | t1 | t2 | t1 | t2 |
1 | 5 | 5 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – |
2 | 7 | 7 | 0 | 0 | 0 | −1 | 0 | 0 | 0 | 0 | 0 | – |
3 | 5 | 5 | 2 | 5 | 0 | 2 | 0 | 2 | 0 | 0 | 5 | – |
4 | 7 | 7 | 7 | 8 | −7 | 0 | 2 | 2 | 3 | −2 | 0 | – |
5 | 5 | 5 | 6 | 4 | 0 | 3 | 2 | 5 | 0 | 1 | 3 | – |
6 | 5 | 5 | 5 | 8 | −3 | 5 | 2 | 4 | 0 | 8 | 2 | – |
7 | 8 | 3 | 3 | 3 | 0 | 3 | 3 | 8 | 0 | 3 | 4 | – |
8 | 8 | 5 | 2 | 7 | −8 | 0 | 0 | 3 | 3 | 5 | 3 | – |
9 | 5 | 3 | 0 | 4 | 0 | 0 | 0 | 4 | 0 | 1 | 3 | – |
10 | 8 | 5 | 0–1 | 7 | 0 | 2 | 2 | 5 | 0 | 3 | 2 | – |
11 | 3 | 3 | 0 | 0 | 0 | 5 | 2 | 9 | 0 | 0 | 0 | – |
12 | 5 | 3 | 0 | 7 | −5 | 4 | 3 | 8 | 0 | 2 | 3 | – |
13 | 6 | 3 | 0 | 0 | −5 | 2 | 2 | 5 | 0 | 1 | 5 | – |
14 | 5 | 3 | 0 | 6 | −3 | 2 | 0 | 7 | 0 | 1 | 0 | – |
15 | 5 | 5 | 2 | 3 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | – |
16 | 5 | 3 | 0 | 8 | −9 | 2 | 1 | 2 | 0 | 2 | 3 | – |
17 | 5 | 5 | 2 | 7 | 0 | 0 | 0 | 3 | 0 | −2 | 1 | – |
18 | 5 | 5 | 1 | 9 | 0 | 2 | 0 | 6 | 0 | 1 | 0 | – |
19 | 5 | 4 | 0 | 4 | 0 | 0 | 2 | 8 | 0 | 0 | 2 | – |
20 | 5 | 5 | −7 | 8 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | – |
*At time treatment onset is indicated.
Note that treatment was stopped after 5 weeks in patient 3 but subsequent long-term effects were assessed; no long-term data are available for patient 6.