Table 2 Effects of intranasal insulin administration as assessed with a questionnaire on developmental progress after 6 weeks (time t1) and 12 months (time t2)13
Patient123456
SexMaleFemaleFemaleFemaleMaleFemale
Age*3 years16 months8.5 years9.5 years5.5 years26 months
Questionst1t2t1t2t1t2t1t2t1t2t1t2
155370000000
277000−100000
355250202005
47778−70223−20
555640325013
65558−3524082
783330338034
88527−8003353
953040004013
10850–170225032
1133000529000
125307−5438023
136300−5225015
145306−3207010
1555230014000
165308−9212023
17552700030−21
1855190206010
1954040028002
2055−780002010
  • *At time treatment onset is indicated.

  • Note that treatment was stopped after 5 weeks in patient 3 but subsequent long-term effects were assessed; no long-term data are available for patient 6.