Table 5 Caspase-7 somatic mutations in different cancers
Tumour typeTotal case numbersCases with caspase-7 mutationsMutation siteNucleotide change (predicted amino acid change)
Colon adenocarcinoma139902Exon 2127 C to T (Arg 43 stop)
Exon 3384 A to G (no change)
Oesophageal squamous cell carcinoma139501Intron 1IVS 1 C -3 to T (splice defect)
Laryngeal squamous cell carcinoma139331Exon 2209 G to A (Cys 70 Tyr)