Tumour type | Total case numbers | Cases with caspase-7 mutations | Mutation site | Nucleotide change (predicted amino acid change) |
Colon adenocarcinoma139 | 90 | 2 | Exon 2 | 127 C to T (Arg 43 stop) |
Exon 3 | 384 A to G (no change) | |||
Oesophageal squamous cell carcinoma139 | 50 | 1 | Intron 1 | IVS 1 C -3 to T (splice defect) |
Laryngeal squamous cell carcinoma139 | 33 | 1 | Exon 2 | 209 G to A (Cys 70 Tyr) |