*After the molecular analysis, we discovered that eight index cases, initially considered as originating from eight independent families, corresponded to four unrelated families. Furthermore, we missed accurate clinical information for one family harbouring a TP53 mutation and we have not included this family to describe the tumour spectrum presented in this table. This explains why the number of index cases presented here is 85 and not 82, as presented in the results. †Frequency of tumours detected in index cases and in relatives carrying the TP53 familial mutation