Table 1 Demographics and clinical factors in 102 adult subjects with 22q11.2DS and 162 unaffected siblings
Subjects with 22q11.2 DS (n = 102)Unaffected siblings (n = 162)Analyses
n%n%Statisticdfp Value
Sex (% male)4443.17747.5χ2 = 0.4910.49
Major CHD (%)3938.20χ2 = 72.71<0.0001
Schizophrenia (%)4645.121.2χ2 = 81.01<0.0001
Mean (SD) age at last follow-up of living (years)*32.7 (9.9)36.1 (12.2)t = 2.362170.02
  • CHD, congenital heart disease.

  • *n = 90 subjects with 22q11.2DS.