Table 3 Stratification of SPRN genotypes in patients with sporadic Creutzfeldt–Jakob disease
Genotype c.20ControlsCJD
MMMVVV
TT3751315029
TC405983141
CC811688
p Value–0.0070.0380.67

  • sCJD, sporadic Creutzfeldt–Jakob disease.

  • Because SPRN SNPs at positions intron 1 5′-11 and c.20 show complete linkage, the genotypes shown are representative of either genotype 5′-11A/5′-11G, or c.20T/c.20C.