Table 2

 Lifetime risk of cancer reported in families with an identified mismatch repair mutation

Colorectal cancer (men)28–75%
Colorectal cancer (women)24–52%
Endometrial cancer27–71%
Ovarian cancer3–13%
Gastric cancer2–13%
Urinary tract cancer1–12%
Brain tumour1–4%
Bile duct/gallbladder cancer2%
Small-bowel cancer4–7%