Table 2

 Main features of the groups of patients based on renal pathology data

GN C3 with MPGN (n = 13)GN C3 without MPGN (n = 6)
C3NeF, C3 nephritic factor; CrCl, creatinine clearance; ESRD, end stage renal disease; F, female; FH, factor H; FI, factor I; GN C3, glomerulonephritis with isolated C3 deposits; M, male; MPGN, membranoproliferative glomerulonephritis; Puria, proteinuria.
*Median values.
†Excluding patient No 15 with C3 NeF and FH mutation.
Age (y)*2626
Sex (F/M)6/74/2
Puria (g/day)*1.70.3
CrCl (ml/min)*5466.3
Follow up (y)*95
ESRD3/130/6
Decreased circulating C3 level5/132/6
C3NeF5/131/6†
FH, FI or MCP mutations2/134/6