Clinical data of the eight subjects
| Patient | Sex | Age* | No. and location of PTX episodes§ | Smoking history | Medical history | Family history of PTX | Family history of carcinoma/neoplasm‡ | No of pulmonary cysts | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| PCOS, polycystic ovary syndrome; PTX, spontaneous pneumothorax. | |||||||||||
| *Age (years) at the first PTX is shown. Age at enrolment in the study is indicated in parentheses. | |||||||||||
| †Age at first visit to our hospital, as patient B5 never had spontaneous pneumothorax. | |||||||||||
| ‡The family members of B3, B6 and B7 had kidney neoplasm, but no detailed information on the pathological subtype was obtained. | |||||||||||
| §L, left-sided pneumothorax; R, right-sided pneumothorax; number of pneumothorax episodes in parentheses. | |||||||||||
| ¶Stage IA adenocarcinoma of the right upper lobe. Resection of right upper lobe with anterolateral thoracotomy was performed. | |||||||||||
| B1 | F | 23 (30) | L (1) R (1) | Never | Endometriosis, PCOS, ovarian cyst, lipoma | Brother, aunt | Grandfather, uncle (no details), grandmother (colon) | 23 | |||
| B2 | F | 16 (38) | L (3) R (3) | 20–34 years, 2.2 pack-years | Myoma of the uterus, ureterolithiasis | Cousin | Grandmother (liver) | 134 | |||
| B3 | F | 25 (40) | L (3) R (2) | Never | None | Father, brother | Father (kidney) | 71 | |||
| B4 | F | 49 (83) | Unknown (1) | Never | Pyothorax, myoma of the uterus, chronic pancreatitis, gallstone disease, sinusitis | None | Father (tonsil), mother (liver) | 387 | |||
| B5 | M | 26† (30) | None | 20–22 years, 0.45 pack-years | Colon polyp | None | Grandmother (lung), aunt (oesophageal), mother (uterus), sister (colon polyp) | 552 | |||
| B6 | F | 35 (37) | L (1) R (1) | Never | Myoma of the uterus, gastric polyp | Father, uncle, aunts, cousins | Grandmother (lung), aunt (kidney) | 14 | |||
| B7 | F | 28 (38) | L (2) R (1) | 20–25 years, 0.6 pack-years | Vocal cord nodules, myoma of the uterus, carcinoma of thyroid gland, recurrent tonsillitis | Grandmother, mother | Great-grandmother (stomach), grandmother (uterus), great-uncles and aunts (stomach, breast, thyroid gland, lung), mother (kidney, thyroid gland) | 17 | |||
| B8 | M | 37 (38) | L (0) R (2) | 20–38 years, 72 pack-years | Lung cancer¶ | None | None | 17 | |||