Major distinguishing findings | Lujan syndrome | FG syndrome | ||
---|---|---|---|---|
Tall stature | + | − | ||
Hypernasal voice | + | − | ||
High nasal root | + | − | ||
Long hyperextensible digits | + | − | ||
Macrocephaly | + | ± | ||
Broad thumbs | ± | + | ||
Frontal hair upsweep | – | + | ||
Hypertelorism/telecanthus | – | + | ||
Small ears | – | + | ||
Persistent fetal finger pads | – | + | ||
Horizontal palmar creases | – | + | ||
Syndactyly | – | + | ||
Anal anomalies | – | + | ||
Childhood constipation | – | + | ||
Genitourinary problems | – | + | ||
Spasticity | – | + |
Major findings that overlap | ||||
---|---|---|---|---|
FG, Opitz–Kaveggia syndrome. | ||||
Agenesis of corpus callosum | High narrow palate, dental crowding | |||
Tall prominent forehead | Micrognathia/retrognathia | |||
Downslanting palpebrae | Hypotonia | |||
Strabismus | Seizures | |||
Maxillary hypoplasia | Mental retardation | |||
Open mouth | Behavioural disturbances |