Adjusted* mean FEV1%predicted, and FEV1/FVC in genotypes of the HO1 gene promoter
| HO1 genotype | p for association | p for trend | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L/L+L/M+L/S | M/M | M/S | S/S | |||||||||
| Data are means (95% CI) (cross-sectional analyses). *Multiple linear regression including centre, sex, age, smoking status, and BMI. | ||||||||||||
| ECRHS I (1992) | ||||||||||||
| FEV1%predicted, % | 104.4 (101.7 to 107.2) | 105.1 (103.2 to 106.9) | 105.4 (103.8 to 107.0) | 106.2 (103.6 to 108.7) | 0.81 | 0.33 | ||||||
| FEV1/FVC, % | 85.3 (84.0 to 86.7) | 85.8 (84.9 to 86.6) | 85.3 (84.6 to 86.1) | 86.2 (85.0 to 87.5) | 0.60 | 0.43 | ||||||
| ECRHS I (2000)I | ||||||||||||
| FEV1%predicted, % | 102.7 (99.8 to 105.8) | 104.1 (102.1 to 106.2) | 103.6 (101.8 to 105.4) | 104.9 (102.1 to 107.7) | 0.73 | 0.34 | ||||||
| FEV1/FVC, % | 82.5 (81.2 to 83.7) | 83.8 (82.9 to 84.6) | 83.2 (82.5 to 84.0) | 84.9 (83.8 to 86.1) | 0.02 | 0.008 | ||||||