Table 1

Minor allele frequencies and nominal pointwise association in the different samples

SNP rs#	rs3807383	rs759011	rs1046355	rs10361	rs6598	rs2286899	rs2286898
SNP rs#	[A/C]	[A/G]	[C/T]	[C/G]	[A/G]	[C/T]	[A/C]
All marker positions are in base pairs (bp) according to NT_007914.14 (see electronic information). All assays were in Hardy–Weinberg equilibrium (p>0.05) when tested in 90 unrelated independent healthy controls (Finnish blood donors), genotyped on the Sequenom platform.
MAF, minor allele frequency; T:U, transmitted:untransmitted ratio.
All p values were calculated using TDT (30).
Position (base pairs)	149871806	149877148	149877691	149877891	149878297	149878362	149878624
FIN_CAU (MAF)	0.25	0.47	0.47	0.46	0.45	0.29	0.47
UK_CAU (MAF)	0.27	0.30	0.28	0.29	0.26	0.12	0.30
UK_ASIA (MAF)	0.22	0.39	0.29	0.29	0.30	0.16	0.29
Pointwise association analysis
FIN_CAU trios			0.057 (34:20)	0.068 (37:23)
FIN_CAU sibs		0.025 (n.a.)					0.035 (n.a.)
UK_CAU trios
UK_CAU sibs
UK_ASIA trios		0.039 (14:5)			0.033 (11:3)