Table 1

 Diagnostic criteria for neurofibromatosis 1 (NF1)

(NIH consensus development conference 1988)3
• 6 or more café au lait macules (>0.5 cm in children or >1.5 cm in adults)
• 2 or more cutaneous/subcutaneous neurofibromas or one plexiform neurofibroma
• Axillary or groin freckling
• Optic pathway glioma
• 2 or more Lisch nodules (iris hamartomas seen on slit lamp examination)
• Bony dysplasia (sphenoid wing dysplasia, bowing of long bone ± pseudarthrosis)
• First degree relative with NF1