Table 5

CFHR5 SNPs in patients segregating MPGN II/DDD

Promoter−249T→CPromoter−20T→CIVS175T→AEx 2P46SIVS258C→T
Allele frequencies (f1 and f2) and number of patients by genotype are shown.
rs9427661rs9427662rs3748557rs12097550rs12097550
MPGN2MPGN2MPGN2MPGN2MPGN2
TT21TT21TT16CC19CC16
TC1TC1TA5CT3CT5
CC0CC0AA1TT0TT1
Sum2222221922
f10.98T0.98T0.84T0.93P0.84C
f20.02C0.02C0.16A0.07S0.16T
At risk haplotypeTTTCC
MPGN2-02T,TT,TT,TC,CC,C
MPGN2-03T,TT,TT,TC,CC,C
MPGN2-07T,TT,TT,TC,CC,C
MPGN2-09T,TT,TA,TC,CC,T
MPGN2-10T,TT,TT,TC,CC,C
MPGN2-11T,TT,TA,TC,CC,T
MPGN2-12T,TT,TT,TC,CC,C
MPGN2-13T,TT,TA,TC,TC,T
MPGN2-14T,TT,TA,AC,CT,T
MPGN2-15T,TT,TT,TC,TC,C
MPGN2-16C,TC,TA,TC,CC,T
MPGN2-17T,TT,TT,TC,CC,C
MPGN2-18T,TT,TA,TC,CC,T
MPGN2-19T,TT,TT,TC,CC,C
MPGN2-20T,TT,TT,TC,TC,C
MPGN2-21T,TT,TT,TC,CC,C
MPGN2-22T,TT,TT,TC,CC,C
MPGN2-23T,TT,TT,TC,CC,C
MPGN2-24T,TT,TT,TC,CC,C
MPGN2-27T,TT,TT,TC,CC,C
MPGN2-29T,TT,TT,TC,CC,C
MPGN2-30T,TT,TT,TC,CC,C