Table 4
Coding SNPs associated with MPGN II/DDD and the related short consensus repeat (SCR) of
CFH
SNP
SCR
Function of SCR
CRP, C-reactive protein.
Exon 2 I62V
1
Interaction with C3b
Exon 9 Y402H
7
Heparin binding
Interaction with CRP
Exon 10 A473A
8
Interaction with CRP