Table 2

CFH SNPs in patients segregating MPGN II/DDD

Ex2I62VIVS2−18insTTEx7A307AIVS7−53G→TEx9Y402HEx10A473AEx13Q672QIVS15−30C→AEx18D936EIVS18−89T→CEx20N1050Y
Allele frequencies (f1 and f2) and number of patients by genotype are shown.
rs800292rs1061147rs1061170rs2274700rs3753396rs1065489
MPGN2MPGN2MPGN2MPGN2MPGN2MPGN2MPGN2MPGN2MPGN2MPGN2MPGN2
GG20(T)9(T)920CC3GG8CC9GG18AA13CC8GG13TT19AA21
GA2(T)11(T)92CA10GT10CT10GA4AG9CA10GT9TC3AT1
AA0(T)11(T)110AA9TT4TT3AA0GG0AA4TT0CC0TT0
Sum2222222222222222222222
f10.95G0.95 (T)90.64A0.59G0.36Y0.90G0.80A0.57C0.80G0.93T0.98A
f20.05A0.05 (T)110.36C0.41T0.64H0.10A0.20G0.41A0.20T0.07C0.02T
At risk haplotypeG9AGCGACGTA
MPGN2-1G,G9,9A,CG,TC,TG,GG,AC,AG,TT,TA,A
MPGN2-2G,G9,9C,CT,TT,TG,GG,AC,AG,TT,TA,A
MPGN2-7G,G9,9A,CG,TC,TG,GG,AC,AG,TT,TA,A
MPGN2-9G,G9,9A,CG,TC,TG,GG,AC,AG,TT,TA,A
MPGN2-10G,G9,9A,CG,TC,TG,GA,AC,AG,TT,TA,A
MPGN2-11G,G9,9A,CG,TC,TG,AA,AC,AG,GT,CA,T
MPGN2-12G,G9,9A,AT,TC,CG,GA,AC,CG,GT,TA,A
MPGN2-13G,G9,9A,CG,TC,TG,GG,AC,AG,TT,TA,A
MPGN2-14G,G9,9A,CG,TC,TG,GG,AC,AG,TT,TA,A
MPGN2-15G,G9,9A,AG,GC,CG,GA,AC,CG,GT,TA,A
MPGN2-16G,G9,9C,CT,TT,TG,AG,AA,AG,TT,CA,A
MPGN2-17G,G9,9A,AG,GC,CG,GA,AC,CG,GT,TA,A
MPGN2-18G,G9,9A,CG,TC,TG,GG,AC,AG,GT,TA,A
MPGN2-19G,G9,9A,AG,GC,CG,GA,AC,CG,GT,TA,A
MPGN2-20G,G9,9A,AG,GC,CG,GA,AC,CG,GT,TA,A
MPGN2-21G,A9,11C,CT,TT,TG,AG,AA,AG,TT,TA,A
MPGN2-22G,G9,9A,AG,GC,CG,GA,AC,CG,GT,TA,A
MPGN2-23G,G9,9A,AG,GC,CG,GA,AC,CG,GT,TA,A
MPGN2-24G,G9,9A,AG,GC,CG,GA,AC,CG,GT,TA,A
MPGN2-27G,A9,11A,CG,TC,TG,AA,AC,AG,GT,TA,A
MPGN2-29G,G9,9A,AG,GC,CG,GA,AA,AG,GT,TA,A
MPGN2-30G,G9,9A,CG,TC,TG,GA,AA,AG,GT,CA,A