Table 2

 Percentage of spontaneous and diepoxybutane (DEB) induced chromosome breakage in patient and control cell lines

CasesPer cent of breaks per cell
SpontaneousDEB
*The quoted ranges for control and Fanconi anaemia cells are those established by the cytogenetics laboratory at Guy’s Hospital.
Test 1III-10.180.56
Normal control0.040.16
Test 2III-10.110.54
Normal control0.020.04
Control range*(0.00 to 0.14)(0.00 to 0.20)
Affected range*(0.18 to 0.48)(0.44 to 1.25)