Table 3

‚ÄÉMean age of first tumour onset in p53 mutation carriers according to the combined MDM2 SNP309 and p53 codon 72 genotypes

No. of at risk lociCorresponding genotypesNo. of patientsMean age (years)*
*Of first tumour onset.
0T/T + Pro/Pro243.0
1(T/G or G/G + Pro/Pro) or (T/T + Arg/Arg or Arg/Pro)1628.5
2T/G or G/G + Arg/Arg or Arg/Pro2316.9