Mean age of first tumour onset in p53 mutation carriers according to the combined MDM2 SNP309 and p53 codon 72 genotypes
No. of at risk loci | Corresponding genotypes | No. of patients | Mean age (years)* | |||
---|---|---|---|---|---|---|
*Of first tumour onset. | ||||||
0 | T/T + Pro/Pro | 2 | 43.0 | |||
1 | (T/G or G/G + Pro/Pro) or (T/T + Arg/Arg or Arg/Pro) | 16 | 28.5 | |||
2 | T/G or G/G + Arg/Arg or Arg/Pro | 23 | 16.9 |