Mean age of first tumour onset in p53 mutation carriers according to the MDM2 SNP309 or p53 codon 72 genotypes
Genotype | No. of patients | Mean age (years)* | ||||
---|---|---|---|---|---|---|
*Of first tumour onset. | ||||||
MDM2 SNP309 | T/T | 14 | 29.9 | |||
T/G | 19 | 17.8 | ||||
G/G | 8 | 23.3 | ||||
T/G+G/G | 27 | 19.6 | ||||
p53 codon 72 polymorphism | Arg/Arg | 18 | 21.1 | |||
Arg/Pro | 20 | 22.5 | ||||
Pro/Pro | 8 | 34.4 | ||||
Arg/Pro+Arg/Arg | 38 | 21.8 |