Table 5 Frequency of GATA4 sequence variants in 628 patients with CHD
Cardiac defectNon-synonymous variantsSynonymous variants
Patients (n)%Patients (n)%
ASD2/1221.63/1222.5
VSD2/1371.54/1372.9
TOF1/2010.58/2014
D-TGA0/7600/760
DORV0/4502/454.4
TA0/2001/205
IAA0/1100/110
L-TGA0/1000/100
Other0/600/60
Total5/6280.818/6282.9
  • ASD, atrial septal defects; DORV, double-outlet right ventricle; D-TGA, D-transposition of the great arteries; IAA, interrupted aortic arch; L-TGA, L-transposition of the great arteries; TA, truncus arteriosus; TOF, tetralogy of Fallot; VSD, ventricular septal defects.