Table 2

 Proportion of unaffected first-degree relatives of mutation carriers testing negative for the family mutation depending on age

Age at testing (years)Testing positiveTesting negativeProportion negative (%)Assumed proportion negative (%)
The table does not include 17 unaffected female first-degree relatives who tested positive (or were obligate carriers) but had a daughter with breast or ovarian cancer who also tested positive.
18–3975624550
40–5951735960
⩾604268790
Total130161