Table 1

Distribution of tested and untested female first-degree relatives by mutation status regardless of censor dates

	Breast cancer	Ovarian cancer	Breast and ovarian cancer	Unaffected	Total
FDR, first-degree relative.
*Positive mutation status inferred only after death by testing paraffin blocks (n = 19) or by identification as an intervening relative between two proved mutation carriers.
Index	190	48	33	6	277
FDR positive	84	11	11	142	248
FDR positive*	64	43	12	9	128
FDR negative	18	1	0	165	184
FDR unknown	127	57	13	215	412
Total	483	160	69	537	1249