Genotype | Frequency | Family number* | S† | E(S)‡ | Var(S)§ | Z value | p |
---|---|---|---|---|---|---|---|
*Number of nuclear families informative for (with a non-zero contribution to) FBAT analysis; †observed genotype number in the affected offspring; ‡expected genotype number in the affected offspring; §the variance of genotype distribution among the affected offspring. | |||||||
rs3741981 | |||||||
T/T | 0.304 | 401 | 143 | 156 | 89 | −1.351 | 0.177 |
C/T | 0.481 | 568 | 278 | 284 | 142 | −0.504 | 0.615 |
C/C | 0.215 | 346 | 147 | 128 | 75 | 2.161 | 0.031 |
rs10774671 | |||||||
A/A | 0.401 | 446 | 170 | 182 | 101 | −1.193 | 0.233 |
A/G | 0.464 | 551 | 271 | 276 | 138 | −0.383 | 0.701 |
G/G | 0.134 | 269 | 110 | 94 | 57 | 2.185 | 0.029 |
rs3177979 | |||||||
A/A | 0.419 | 443 | 168 | 182 | 101 | −1.345 | 0.179 |
A/G | 0.458 | 543 | 269 | 272 | 136 | −0.215 | 0.830 |
G/G | 0.123 | 260 | 106 | 90 | 55 | 2.157 | 0.031 |