Baseline characteristics of patients with definite familial hypercholesterolaemia, with and without documented coronary heart disease
| CHD negative n = 251 | CHD positive n = 158 | p Value | |
|---|---|---|---|
| BMI, body mass index; CHD, coronary heart disease; DBP, diastolic blood pressure; HDL-chol, high-density lipoprotein-cholesterol; LDL-chol, low-density lipoprotein-cholesterol; N, number of subjects; SBP, systolic blood pressure. | |||
| LDL-chol and HDL-chol values at recruitment are available for all patients. | |||
| *For traits marked (values in parentheses = standard deviations) | |||
| Number of patients with pretreatment cholesterol data available is shown. | |||
| % Male (n) | 42.6 (107) | 65.2 (103) | <0.001 |
| Age (years)* | 44.5 (13.6) | 56.2 (10.3) | <0.001 |
| BMI (kg/m2)* | 23.7 (4.1) | 25.0 (3.5) | 0.004 |
| % ever smokers (n) | 37.8 (95) | 60.8 (96) | <0.001 |
| % current smokers (n) | 15.1 (38) | 11.4 (18) | 0.28 |
| SBP (mm Hg)* | 124.3 (16.0) | 130.7 (19.9) | <0.001 |
| DBP (mm Hg)* | 76.8 (9.8) | 78.6 (12.4) | 0.12 |
| Pretreatment cholesterol (mmol/l)* | 9.89 (1.73) (n = 185) | 10.55 (2.11) (n = 114) | 0.004 |
| Recruitment LDL-chol (mmol/l)* | 4.77 (1.26) | 4.21 (1.23) | <0.001 |
| Recruitment HDL-chol (mmol/l)* | 1.39 (0.35) | 1.28 (0.36) | 0.004 |