Frequency distributions of p53 haplotypes (intron 3 insertion and codon 72 polymorphism) in control and OAG subjects
| Del-Arg | Del-Pro | Ins-Arg | Ins-Pro | p Value* | |
|---|---|---|---|---|---|
| Values are n (%). | |||||
| *χ2 test between disease subgroup and control cohort. | |||||
| Arg, arginine 72 polymorphism; Del, absence of the 16 bp insertion on intron 3; HTG, high tension glaucoma; Ins, presence of the 16 bp insertion on intron 3; NTG, normal tension glaucoma; OAG, open angle glaucoma; Pro, proline 72 polymorphism. | |||||
| Control | 268 (75.3%) | 38 (10.7%) | 7 (2.0%) | 43 (12.1%) | |
| HTG | 412 (72.8%) | 66 (11.7%) | 5 (0.9%) | 83 (14.7%) | 0.333 |
| NTG | 85 (68.6%) | 19 (15.3%) | 1 (0.8%) | 19 (15.3%) | 0.292 |
| Total | 765 (73.1%) | 123 (11.8%) | 13 (1.2%) | 145 (13.9%) | |