Frequency and age at onset of specific signs and symptoms of Fabry disease in females (n = 248)
| Frequency | Age at onset | |||
|---|---|---|---|---|
| Proportion of population (%) | Number of patients | Mean±SD | Number of patients | |
| LV, left ventricular; TIA, transient ischaemic attack. | ||||
| Cerebrovascular | 25 | 61 | 38.8±17.5 | 35 |
| Stroke | 7 | 18 | 49.9±14.5 | 15 |
| TIA | 7 | 17 | 42.9±14.6 | 13 |
| Neurological | 77 | 192 | 16.0±14.0 | 99 |
| Pain attacks | 57 | 142 | 16.6±15.0 | 98 |
| Chronic pain | 32 | 80 | 20.7±14.5 | 55 |
| Cardiac | 59 | 147 | 33.5±18.1 | 66 |
| Chest pain | 15 | 37 | 41.5±16.3 | 16 |
| Palpitations | 20 | 50 | 41.6±15.3 | 30 |
| LV hypertrophy | 26 | 65 | 50.4±11.3 | 35 |
| Renal/urinary | 40 | 100 | 37.3±16.6 | 61 |
| Proteinuria | 35 | 86 | 38.8±18.2 | 59 |
| Dialysis | 1 | 40.0 | 1 | |
| Transplants | 1 | 2 | 40.1±1.2 | 2 |
| Gastrointestinal | 50 | 124 | 21.4±16.6 | 65 |
| Diarrhoea | 19 | 46 | 19.0±15.8 | 23 |
| Constipation | 15 | 37 | 23.3±18.5 | 22 |
| Auditory | 48 | 119 | 29.8±18.7 | 71 |
| Tinnitus | 29 | 71 | 27.9±15.9 | 46 |
| Vertigo | 32 | 80 | 34.1±17.9 | 58 |
| Sudden deafness | 4 | 9 | 36.5±20.0 | 8 |
| Ophthalmological | 50 | 123 | 31.1±18.9 | 76 |
| Cornea verticillata | 40 | 99 | 32.3±20.2 | 72 |
| Tortuous vessels | 6 | 14 | 34.4±23.6 | 8 |
| Posterior subcapsular cataract | 2 | 6 | 61.3±8.7 | 3 |
| Dermatological | 44 | 108 | 29.0±16.1 | 60 |
| Angiokeratomas | 40 | 100 | 28.6±15.5 | 59 |
| Telangiectasia | 8 | 19 | 29.3±17.9 | 10 |