Major haplotypes of PRNP SNPs and their frequencies in cases and controls
| Over-represented in: | Haplotypes of PRNP | Frequency | p | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1368 | 12533 | 13436 | 16987 | 22976 | A117A | M129V | 28878 | 34296 | Cases | Controls | |||||||||||||||
| Controls | 1 | T | C | C | G | G | A | G | C | A | 9.08% | 16.46% | <0.00001 | ||||||||||||
| 2 | T | C | C | G | G | A | G | T | A | 2.36% | 5.16% | 0.0002 | |||||||||||||
| 3 | T | C | C | G | G | A | G | C | G | 1.69% | 4.17% | 0.0002 | |||||||||||||
| T | C | C | G | G | A | G | C | — | Haplotype A in Mead etal10 | ||||||||||||||||
| Cases | 4 | C | C | T | T | A | A | A | T | A | 13.99% | 10.56% | 0.007 | ||||||||||||
| 5 | C | C | T | T | A | A | A | T | G | 33.03% | 26.26% | 0.0001 | |||||||||||||
| C | C | T | T | A | A | A | T | — | Haplotype B in Mead etal10 | ||||||||||||||||