The association between rapidly progressing fibrosis and possession of increasing number of progression associated alleles
| No. of profibrotic | Rate of fibrosis progression | p | Odds ratio (95% CI) | Adjusted p† | Adjusted odds | |
|---|---|---|---|---|---|---|
| genotypes | Slow, n (%) | Rapid, n (%) | ratio† (95% CI) | |||
| *Row percentages; †variables considered in the analysis included age at infection, gender, viral genotype, and BMI. | ||||||
| 95% CI, 95% confidence interval. | ||||||
| <3 | 13 (72.2) | 5 (27.8) | ||||
| ⩾3 | 46 (39) | 72 (61) | 0.008 | 4.1 (1.4 to 12.8) | 0.002 | 9.1 (2.2 to 37.3) |
| ⩾4 | 22 (28.2) | 56 (71.8) | 0.0005 | 6.6 (2.1 to 12.8) | <0.0001 | 15.5 (3.4 to 70) |
| ⩾5 | 5 (15.2) | 28 (84.8) | <0.0001 | 14.6 (3.6 to 59.3 | <0.0001 | 24.1 (4.3 to 136) |