Table 2

 Odds ratios and (corrected) 95% confidence intervals for the association of the allele/genotype of the markers with cervical neoplasia risk

LocusAlleleControlsOR (95% CI)All patientsOR (95% CI)CINOR (95% CI)
G511525221127/1887 (6.7%)1*76/1945 (3.9%) 0.56 (0.36 to 0.89) 23/522 (4.4%)0.64 (0.31 to 1.30)
MICA184996/1945 (50.9%)1*1073/1925 (55.7)1.20 (0.98 to 1.46)281/518 (54.2%)1.13 (0.83 to 1.53)
Genotype
G511525221 carriers77/658 (11.7%)1*69/970 (7.1%) 0.58 (0.34 to 0.99) 23/261 (8.8%)0.73 (0.34 to 1.57)
MICA184 HZ180/687 (26.2)1*310/961 (32.3%)1.34 (0.95 to 1.89)74/259 (28.6%)1.13 (0.68 to 1.86)
LocusAlleleAll carcinomasOR (95% CI)SCCOR (95% CI)ACOR (95% CI)
Significant numbers in bold.
*Reference category.
AC, adenocarcinoma; CI, confidence interval; CIN, cervical intraepithelial neoplasia; HZ, homozygous; OR, odds ratio; SCC, squamous cell carcinoma.
G51152522148/1322 (3.6%) 0.52 (0.31 to 0.89) 33/1012 (3.3%) 0.47 (0.25 to 0.86) 15/310 (4.8%)0.70 (0.30 to 1.67)
MICA184738/1300 (56.8%) 1.25 (1.00 to 1.56) 576/994 (57.9) 1.31 (1.03 to 1.67) 162/306 (52.8%)1.07 (0.73 to 1.56)
Genotype
G511525221 carriers42/659 (6.4%) 0.51 (0.28 to 0.95) 28/504 (5.6%) 0.44 (0.22 to 0.90) 14/155 (9.0%)0.75 (0.29 to 1.91)
MICA184 HZ222/649 (34.2) 1.46 (1.01 to 2.12) 173/496 (34.9%) 1.51 (1.02 to 2.24) 49/153 (32.0%)1.33 (0.73 to 2.41)