Genotype distribution by gender of TNFβ and TNFα −308 genes in group A (n = 27) compared to group B (n = 102)
| Genotype | Group A male (n, %) | Group A female (n, %) | Group B male (n, %) | Group B female (n, %) | |
|---|---|---|---|---|---|
| TNFβ | 1/1 | 1 (6, 7%) | 0 | 10 (17, 5%) | 8 (17, 8) |
| 1/2 | 2 (13, 3%) | 6 (50%) | 22 (38, 6%) | 17 (37, 8) | |
| 2/2 | 12 (80%) | 6 (50%) | 25 (43, 9%) | 20 (44, 5) | |
| Total | 15 (100%) | 12 (100%) | 57 (100%) | 45 (100) | |
| p Value v control | p<0.04 | p<0.28 | |||
| TNFα promoter −308 | 1/1 | 12 (80%) | 7 (58, 3%) | 37 (64, 9%) | 31 (68, 9%) |
| 1/2 | 2 (13, 3%) | 5 (41, 7%) | 18 (31, 6%) | 11 (24, 4%) | |
| 2/2 | 1 (6, 7%) | 0 | 2 (3, 5%) | 3 (6, 7%) | |
| Total | 15 (100%) | 12 (100%) | 57 (100%) | 45 (100%) | |
| p Value v control | p<0.35 | p<0.38 |