Comparison of findings among patients with NF1 with different estimated numbers of dermal neurofibromas
| Number of external neurofibromas | ||||||
|---|---|---|---|---|---|---|
| *Serum 25-hydroxyvitamin D concentration. | ||||||
| 10–99 | 100–999 | ⩾1000 | ||||
| Number of patients | 16 | 24 | 7 | |||
| Age in years (mean (SD)) | 37.2 (10.7) | 43.2 (7.5) | 50.4 (7.8) | |||
| Statistical significance | F2,44 = 5.7, p = 0.006 | |||||
| Vitamin D* (ng/mL) | ||||||
| Geometric mean (SD) | 19.5 (1.4) | 13.1 (1.5) | 8.2 (1.6) | |||
| Statistical significance | F2,44 = 12.7, p<0.0001 (unadjusted) | |||||
| F2,43 = 9.7, p = 0.0003 (adjusted for age) | ||||||
| Proportion <20 ng/mL | 9/16 (56%) | 20/24 (83%) | 6/7 (86%) | |||