Table 1

 Comparison of findings in patients with NF1 and controls

PatientsControlsStatistical test of difference
*Serum 25-hydroxyvitamin D concentration. NS, not significant.
Number studied5558
Age in years (mean (SD))40.3 (10.4)36.0 (8.8)t111 = 2.38, p = 0.019
Female:male ratio33:2238:20NS
Vitamin D* (ng/mL)
    Mean (SD)15.7 (7.5)35.5 (17.1)t111 = 7.91, p<<0.0001
    Geometric mean (SD)14.0 (1.6)31.4 (1.7)t111 = 8.66, p<<0.0001
    Proportion <20 ng/mL72%21%χ2 = 30.8, p<<0.0001