Table 1

Chromosomal deletion detected by microarray expression analysis

Cell	Karyotype*	Baseline distribution†	Underexpression distribution‡	Odds ratio§	χ²¶	p**	χ² fraction††
Karyotypes were provided by Coriell Cell Repositories/NIGMS. †The fraction of all assayed transcripts localised to the chromosomal deletion region in column 2; ‡fraction of underexpressed transcripts localised to the chromosomal deletion region in column 2. §Odds ratio: odds of underexpression for transcripts from the chromosomal deletion region in column 2 relative to the odds of all transcripts originating from that region.; ¶χ²: difference between observed incidence of underexpression and incidence expected based on homogenous underexpression rates across all chromosomes.; *p value: probability of χ² test statistic ⩾ that observed in column 6 by chance alone under the assumption of homogenous underexpression across chromosomes; ††χ² fraction: fraction of the genomewide departure from expectation (χ² (23 df) in column 6) that can be attributed to the specific DNA listed in column 2.
GM03240	46, XY, del(7)(q34)	0.00517	0.28500	3.13	80.82	<0.000001	0.717
GM00870	46, XX, del(9)(p21)	0.00967	0.17647	2.10	26.15	<0.000001	0.207
GM03047	46, XY, del(10)(p11.2)	0.00742	0.24042	3.54	121.69	<0.000001	0.730