The result of ANOVA and regression analysis (Reg.) of anthropometric and metabolic traits for the AGTR1 A1166C polymorphism in 240 men and 138 women
| Men | p Value | Women | p Value | Combined analysis | p Value | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AA | AC | CC | ANOVA | Reg. | AA | AC | CC | ANOVA | Reg. | AA | AC | CC | ANOVA | Reg. | |
| Mean values of each genotype groups are shown; standard deviations (SD) are given in parentheses. Geometric means and SDs were used for glucose, insulin, cholesterol, triglyceride, and fibrinogen values. p Values are on 2 df from ANOVA and 1 df from regression on allele unadjusted unless mentioned. The mentioned analysis was adjusted for gender. | |||||||||||||||
| BMI | 26.9 | 27.4 | 25.2 | 0.03 | 0.61 | 26.3 | 27.3 | 25.5 | 0.25 | 0.56 | 26.7 | 27.4 | 25.3 | 0.01 | 0.99 |
| (kg/m2) | (3.3) | (3.4) | (3.0) | (3.6) | (4.7) | (1.9) | (3.4) | (4.0) | (2.6) | ||||||
| Waist to hip | 0.94 | 0.94 | 0.90 | 0.01 | 0.01 | 0.80 | 0.79 | 0.77 | 0.48 | 0.40 | 0.89 | 0.88 | 0.86 | 0.004 | 0.013 |
| Ratio | 0.05 | 0.05 | 0.05 | 0.06 | 0.05 | 0.04 | 0.09 | 0.09 | 0.08 | ||||||
| Waist circum- | 99.2 | 98.4 | 91.5 | 0.008 | 0.02 | 82.6 | 83.9 | 76.5 | 0.09 | 0.61 | 93.7 | 92.5 | 86.7 | 0.001 | 0.02 |
| ference (cm) | (10.2) | (9.0) | (8.2) | (9.0) | (9.6) | (2.9) | (12.6) | (11.7) | (9.9) | ||||||
| Adult weight | 80.4 | 80.3 | 73.6 | 0.06 | 0.12 | 67.7 | 70.5 | 62.1 | 0.07 | 0.86 | 76.2 | 76.3 | 69.9 | 0.008 | 0.24 |
| (kg) | (11.5) | (10.8) | (11.0) | (9.8) | (12.0) | (5.3) | (12.5) | (12.3) | (10.9) | ||||||
| Height | 1.73 | 1.71 | 1.71 | 0.07 | 0.03 | 1.60 | 1.61 | 1.56 | 0.11 | 0.42 | 1.67 | 1.67 | 1.67 | 0.07 | 0.02 |
| (m) | (0.07) | (0.05) | (0.07) | (0.06) | (0.05) | (0.06) | (0.09) | (0.07) | (0.1) | ||||||
| Fasting glucose | 6.1 | 5.9 | 5.6 | 0.08 | 0.03 | 5.7 | 5.7 | 5.8 | 0.89 | 0.82 | 6.0 | 5.8 | 5.6 | 0.18 | 0.07 |
| (mmol/l) | (1.2) | (1.2) | (1.1) | (1.1) | (1.2) | (1.1) | (1.2) | (1.2) | (1.1) | ||||||
| Glucose at 30 min | 9.7 | 9.3 | 8.2 | 0.01 | 0.008 | 8.8 | 8.7 | 8.1 | 0.58 | 0.50 | 9.4 | 9.1 | 8.2 | 0.01 | 0.01 |
| (mmol/l) | (1.3) | (1.2) | (1.2) | (1.2) | (1.2) | (1.2) | (1.3) | (1.2) | (1.2) | ||||||
| Glucose at 120 min | 6.8 | 6.3 | 5.7 | 0.06 | 0.02 | 7.1 | 7.1 | 6.6 | 0.73 | 0.73 | 6.9 | 6.6 | 6.0 | 0.08 | 0.03 |
| (mmol/l) | (1.4) | (1.4) | (1.2) | (1.3) | (1.3) | (1.4) | (1.3) | (1.4) | (1.3) | ||||||
| Insulin at 0 min | 42.7 | 40.8 | 27.4 | 0.04 | 0.05 | 48.4 | 42.3 | 50.1 | 0.34 | 0.41 | 44.6 | 41.4 | 33.5 | 0.08 | 0.04 |
| (pm/l) | (1.2) | (1.8) | (2.0) | (1.7) | (1.8) | (1.2) | (1.9) | (1.8) | (1.9) | ||||||
| Insulin at 30 min | 271.3 | 266.7 | 238.2 | 0.74 | 0.53 | 248.3 | 249.9 | 353.0 | 0.24 | 0.30 | 263.3 | 259.6 | 271.6 | 0.95 | 0.96 |
| (pm/l) | (1.9) | (1.9) | (1.6) | (1.7) | (1.8) | (1.6) | (1.8) | (1.9) | (1.6) | ||||||
| Insulin at 120 min | 161.9 | 135.7 | 121.4 | 0.21 | 0.08 | 231.0 | 238.1 | 223.8 | 0.94 | 0.92 | 183.1 | 172.6 | 151.7 | 0.35 | 0.15 |
| (pm/l) | (2.3) | (2.4) | (1.8) | (1.9) | (1.9) | (1.7) | (2.2) | (2.3) | (1.9) | ||||||
| Systolic BP | 165.0 | 162.9 | 156.9 | 0.30 | 0.15 | 156.4 | 156.0 | 161.3 | 0.82 | 0.78 | 162.1 | 160.1 | 158.3 | 0.61 | 0.39 |
| (mmHg) | (21.8) | (20.8) | (16.8) | (21.2) | (23.6) | (17.1) | (21.9) | (22.2) | (16.7) | ||||||
| Pulse pressure | 74.8 | 72.7 | 69.2 | 0.29 | 0.12 | 75.1 | 72.8 | 76.9 | 0.61 | 0.70 | 74.9 | 72.7 | 71.7 | 0.32 | 0.14 |
| (mmHg) | (16.1) | (14.6) | (13.4) | (14.6) | (15.8) | (17.6) | (15.5) | (15.0) | (15.0) | ||||||
| Fasting cholesterol | 6.7 | 6.5 | 6.2 | 0.32 | 0.16 | 7.0 | 7.2 | 6.2 | 0.07 | 0.72 | 6.8 | 6.8 | 6.2 | 0.08 | 0.18 |
| (mmol/l) | (1.2) | (1.2) | (1.2) | (1.2) | (1.2) | (1.2) | (1.2) | (1.2) | (1.2) | ||||||
| Fasting TG | 1.5 | 1.4 | 1.3 | 0.41 | 0.19 | 1.2 | 1.4 | 1.0 | 0.04 | 0.72 | 1.4 | 1.4 | 1.2 | 0.19 | 0.28 |
| (mmol/l) | (1.7) | (1.7) | (1.5) | (1.6) | (1.5) | (1.4) | (1.7) | (1.6) | (1.5) | ||||||
| Fasting fibrinogen | 309.5 | 295.7 | 302.9 | 0.28 | 0.22 | 302.9 | 283.8 | 267.1 | 0.01 | 0.002 | 307.4 | 290.9 | 290.5 | 0.03 | 0.01 |
| (g/l) | (1.2) | (1.3) | (1.2) | (1.2) | (1.1) | (1.1) | (1.2) | (1.2) | (1.2) | ||||||