Transmission of VEGF alleles from heterozygous parents to TOF affected children
Gene variation | Risk allele | Allele frequency (%) | Transmitted risk alleles | Untransmitted risk alleles | χ2 | p Value |
---|---|---|---|---|---|---|
The exact number of transmitted and untransmitted risk alleles with their relative frequency between brackets is indicated. | ||||||
−2578 C/A | −2578A | 0.49 | 87 (0.59) | 61 (0.41) | 4.6 | 0.016 |
−1154 G/A | −1154A | 0.32 | 73 (0.59) | 50 (0.41) | 4.3 | 0.019 |
−634 G/C | −634G | 0.66 | 77 (0.59) | 54 (0.41) | 4.1 | 0.022 |