Table 2

BRCA2 mutation carrier offspring data by mutation position

	Families	Individuals	Total offspring	Female offspring	p Value
*Includes 6174delT.
All BRCA2	99	174	268	145 (54.1%)
6174delT	47	71	117	72 (61.5%)	0.032
Other BRCA2	52	103	151	73 (48.3%)
Exons 1–11*	82	138	201	118 (58.7%)	0.009
Exons 12–27	17	36	67	27 (40.3%)
Exons 1–11 excluding 6174delT	35	67	84	46 (54.7%)	0.077
Exons 12–27	17	36	67	27 (40.3%)