Table 3

 Expression of STRA13, CA IX, and HIF-α1 in human tumours

No of positive cases/total No of cases studiedNo of positive cases (%) associated with hypoxia (necrosis)
STRA13* (nuclear)CAIXHIF-α1* (nuclear)STRA13* (nuclear)CAIXHIF-α1* (nuclear)
*The positive staining is limited to nuclear reactivity.
Ca, carcinoma; LMP, low malignancy potential.
Cervical carcinomas
    Squamous cell Ca4/1210/1210/121 (8)10 (83)10 (83)
    Adenocarcinoma4/44/40/4000
    Endometrial adenocarcinoma3/32/33/3000
Ovary
    Adenocarcinoma10/149/149/1404 (29)4 (29)
    Mucinous tumours of LMP4/44/41/4000
Breast
    Ductal Ca5/53/53/503 (60)3 (60)
    Lobular Ca4/40/40/4000
Colon
    Adenocarcinoma3/1717/173/1705 (29)0
    Adenoma0/33/30/3000
Lung
    Squamous cell Ca1/33/33/31 (33)3 (100)3 (100)
    Adenocarcinoma5/63/64/6000
Kidney/urinary tract
    Renal cell Ca (clear cell)6/109/106/10000
    Transitional cell Ca4/44/44/4000
    Glioblastoma multiforme4/44/41/404 (100)1 (25)
    Mesothelioma1/22/20/2000