The distribution of STRA13 and CA IX protein expression in normal adult human tissues
STRA13 | CA IX | |||
---|---|---|---|---|
Nuclear staining | Cytoplasmic staining | Membrane/cytoplasm | ||
Lining cells of body cavity | ||||
Mesothelial cells (serous membrane) | Focal | Negative | Diffuse | |
Coelomic epithelium (surface of the ovary) | Focal | Negative | Diffuse | |
Squamous mucosa of all organs | Variable | Diffuse | Negative | |
Oral mucosa, tonsil, larynx | Rare | Diffuse | Negative | |
Tongue, oesophagus | Focal | Diffuse | Negative | |
Anus/vagina | Rare | Diffuse | Negative | |
Ectocervix | Diffuse | Focal | Negative | |
Myoepithelial cells of all organs | ||||
Salivary glands, breast, prostate gland | Negative | Diffuse | Negative | |
Skin | ||||
Epidermis, rare | Diffuse | Focal | ||
Sweat/sebaceous glands | Rare | Diffuse | Negative | |
Hair follicle | Rare | Diffuse | Focal | |
Upper/lower respiratory system | ||||
Respiratory epithelial cells | Focal | Negative | Negative | |
Reactive reserve cells | Focal | Negative | Rare | |
Type II alveolar cells | Diffuse | Weak | Negative | |
Alveolar macrophges | Rare | Diffuse | Negative | |
Gastrointestinal system | ||||
Gastric/duodenal surface glands | Diffuse | Negative | Diffuse | |
Crypt cells of duodenum/small intestine, appendix | Negative | Negative | Diffuse/focal | |
Crypt cells of large intestine | Negative | Negative | Rare | |
Surface glandular cells of large intestine | Negative | Diffuse | Negative | |
Pancreas | ||||
Ductal cells | Focal | Negative | Negative | |
Acinar cells | Focal | Negative | Negative | |
Gallbladder/biliary tract | Diffuse | Negative | Diffuse | |
Genitourinary system | ||||
Kidney | ||||
Proximal convoluted ducts | Variable | Negative | Negative | |
Distal convoluted ducts | Variable | Diffuse | Negative | |
Collecting duct | Negative | Variable | Negative | |
Renal pelvis/ureter/bladder | ||||
Transitional cells | Focal | Negative | Negative | |
Prostate gland | Negative | Negative | Negative | |
Testis | ||||
Ductular unites/epididymis | Focal | Negative | Negative | |
Germ cells | Rare | Negative | Negative | |
Uterine cervix | ||||
Mature squamous cells | Diffuse | Weak/negative | Negative | |
Basal cells of squamous mucosa | Negative | Diffuse | Negative | |
Reactive reserve cells of the glands | Diffuse | Negative | Rare | |
Metaplastic squamous cells | Diffuse | Negative | Rare | |
Uterine endometrial glands | ||||
Proliferative phase | Negative | Negative | Negative | |
Secretory phase | Variable | Negative | Negative | |
Ovary | ||||
Surface coelomic epithelium | Focal | Negative | Diffuse | |
Granulosa/theca cells | Focal | Negative | Negative | |
Breast | ||||
Myoepithelial cells | Negative | Diffuse | Negative | |
Ductal units | Focal | focal | Negative | |
Lobular units | Diffuse | Negative | Negative | |
Lymph node/spleen | ||||
Lymphocytes | Negative | Negative | Negative | |
Macrophages | Negative | weak | Negative | |
Thymus gland | ||||
Lymphocytes | Negative | Negative | Negative | |
Thymocytes | Negative | Diffuse | Negative | |
Central nervous system | ||||
Glial cells | Rare | Rare | Negative | |
Neurone | Diffuse | Diffuse | Negative | |
Choroid plexus | Focal | Focal | Diffuse |