Elastin | – | Tropoelastin deposition78 |
| | Regulation of microfibril formation75 |
LTBP-1 | Fibrillin-LTBP | Sequestering of latent TGFβ102 |
LTBP-2 | Fibrillin-LTBP | Structural role?103 |
LTBP-4 | Fibrillin-LTBP | Sequestering of latent TGFβ102 |
Versican | Proteoglycan (hyalectin) | Link fibrillin-microfibrils to versican/hyaluronan network104 |
Perlecan | Proteoglycan (hyalectin) | Anchoring microfibrils to basement membranes and in the |
| | biogenesis of microfibrils69 |
Heparin/heparan sulfate | Proteoglycan | Binding of related heparan sulfate chains may regulate cell-surface |
| | assembly of fibrillin66 |
Decorin | Small dermatan sulfate proteoglycan | Induction of fibrillin-1 expression in renal fibroblasts and mesangial cells105 |
Biglycan | Small dermatan sulfate proteoglycan | Role in elastogenesis77 |
Fibulin-2 | Fibulin | Mediate/modulate attachment of fibrillin to tropoelastin106 |
Fibulin-5 | Fibulin | Regulation of the initial deposition of tropoelastin on to microfibrils107 |
BMP-7 | Bone morphogenetic protein | Regulation of limb patterning12 |
EMILIN-1 | Elastin-microfibril interface located proteins | Role in elastinogenesis108 |