Small non-fibrillin proteins that are integral parts of fibrillin-rich microfibrils in at least some tissues and developmental stages
| Protein | Chromosome | Potential functions |
|---|---|---|
| MAGP-1 | 1p36.1–p35 | Tropoelastin deposition78 |
| Tropoelastin binding76,89 | ||
| Binding to fibrillin-176,90 | ||
| Binding to fibrillin-291 | ||
| Ternary complex with | ||
| tropoelastin and biglycan77 | ||
| Posttranslational modifications92 | ||
| Ternary complex with | ||
| tropoelastin and decorin93 | ||
| Binding to type VI collagen79 | ||
| Substrate for transglutaminase63 | ||
| MAGP-2 | 12p12.3–p13.1 | Binding to fibrillin-174,90 |
| Binding to fibrillin-274 | ||
| RGD-mediated cell attachment94 | ||
| Interaction with Jagged180 | ||
| AAAP-40 | 5q32–q33.2 | 40 kDa protein95,96 |
| (MAGP-3) | ||
| MFAP1 (AMP) | 15q15–q21 | 54 kDa protein that is processed |
| to a 36 kDa protein97,98 | ||
| MFAP3 | 5q32–q33.1 | 41 kDa serine-rich protein99 |
| MFAP4 | 17p11.2 | Colocalisation to elastic fibres100 |
| (MAGP-36) | Role in elastogenesis101 |